The Genetic Theory of Longevity

Ageing and the physical signs of ageing are something that has become a hot topic of conversation within our society. Scientists are trying to figure out what causes us to age and how to prevent or reverse it. The first step towards unravelling this riddle is genetic testing and gathering information on how our genetics affect our ageing. This is how the genetic theory of ageing came to exist.

The genetic theory of ageing states that a human’s lifespan is greatly influenced by our genetics and the genes we inherit from our forefathers.

What genes are involved in longevity?

There are a variety of genes that have been identified and associated with longevity and here we break down a few of these genes.

CETP is a crucial protein involved in the regulation of high-density lipoprotein (HDL) levels. It may affect susceptibility to age-related diseases, including atherosclerosis and Alzheimer’s Disease. A higher HDL/LDL ratio has been associated with healthier and longer-lived individuals.

Interleukin-6 (IL-6) is an inflammatory cytokine. While inflammation is beneficial while fighting off a disease, it can be harmful when it is excessive, especially in the case of chronic inflammation. If your result is G/G for the Il-6 gene result in the Geneway report, it means you have higher IL-6 sensitivity to inflammatory stimuli. This genotype (G/G) is seen in fewer centenarians.

The COMT gene is responsible for the metabolism of estrogen, catecholamine neurotransmitters, and other compounds. The A/A genotype of the COMT gene is found more frequently among the elderly, suggesting a possible longevity advantage.

The CYP2B6 gene codes for a phase I detoxifying enzyme that is involved in the metabolism of a variety of medications (including cancer treatments) and cholesterol production. The T/T result is indicative of reduced CYP2B6 enzyme function. This genotype is less common in the elderly showing a potential longevity disadvantage due to cancer risk or toxicant exposure.

Preventing Ageing in Genetics

One cannot stop one’s genetics from ageing. Thus, there is no magic pill that can reverse the ageing process; however, there are ways to ensure that you do not age faster than what is dictated by your genetics. Some of the steps you can take to ensure that you do not age prematurely include:

  • Eating healthy foods
  • Ensuring that you do not smoke
  • Trying to avoid drinking too much alcohol
  • Exercising regularly

Other than these basic steps toward healthy living, one can opt for a DNA test that can provide you with more detailed and personalised information about your genetic profile and its tendencies in premature ageing. Once you possess this information you can start to supplement your lifestyle and cosmetic support to maintain a youthful appearance.

How GENERENEW™ Can Help You

GENRENEW™ is an at-home DNA test that can provide you with information on your genetic blueprint and what your anti-ageing skincare routine should consist of. Some of the effects on your skin that can be tested for include skin irritability, detoxification, anti-oxidation, cell renewal, and collagen synthesis.

To find out more about the genetic theory of ageing and how you can do your best to remain youthful, contact us at GENEWAY or find one of our practitioners near you!

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